Ngokocwaningo olushicilelwe kumagazini i-Clinical and Translational Allergy, amayunithi okuhlunga komoya aphathwayo anamazinga anele okulethwa komoya ohlanzekile angasusa ngempumelelo izibungu, izinto ezingezwani nekati nezinja, kanye nezinhlayiyana zomoya ongaphakathi endlini.
Abacwaningi balubiza ngokuthi ucwaningo olubanzi kakhulu, olugxile ekusebenzeni kahle kokuhlunga komoya kwezinhlobonhlobo zezici ezitholakala emoyeni emakamelweni okulala.
"Eminyakeni emibili ngaphambi kocwaningo, abacwaningi abaningana eYurophu kanye nami saba nomhlangano wesayensi mayelana nekhwalithi yomoya kanye nokungezwani komzimba," kusho uJeroen Buters, i-PharmD, i-toxicologist, isekela lomqondisi weSikhungo Sokungezwani komzimba kanye neMvelo, kanye nelungu le-German Centre Munich. Imboni I-Lung Research Center eNyuvesi kanye neHelmholtz Centre itshele i-Healio.
Abacwaningi bahlole i-Dermatophagoides pteronyssinus Der p 1 kanye ne-Dermatophagoides farinaeI-Der f 1 i-allergen ye-dust mite yendlu, i-Fel d 1 cat allergen kanye ne-Can f 1 inja engezwani nenja, konke okungatholakala ezinhlayiyeni ezisemoyeni (PM).
“Wonke umuntu ucabanga ukuthi i-Dermatophagoides pteronyssinus iyisimbuzane esikhiqiza ukungezwani komzimba okuyinhloko emndenini.Hhayi - okungenani hhayi eMunich, futhi mhlawumbe hhayi kwenye indawo.Lapho i-Dermatophagoides farinae, enye imbuzane ehlobene eduze.Cishe zonke iziguli zelashwa ngokukhipha i-D pteronyssinus.Ngenxa yokufana okukhulu phakathi kwabo, lokhu bekulungile,” kusho uButters.
“Futhi, imbuzane ngayinye iphila ngendlela ehlukile, ngakho-ke wazi kangcono ukuthi iyiphi okhuluma ngayo.Eqinisweni, kunabantu abaningi eMunich abazwela u-D. farina kuno-D. pteronyssinus,” waqhubeka..
Abaphenyi benza ukuvakasha kokulawula nokungenelela emzini ngamunye ngezikhathi zamasonto angu-4. Phakathi nokuvakasha kokungenelela, bamele izehlakalo zokuphazamiseka kothuli ngokunyakazisa umcamelo imizuzwana engu-30, isembozo sombhede imizuzwana engu-30, neshidi lombhede imizuzwana engu-60.
Ngaphezu kwalokho, abacwaningi balinganise ukugxila kwe-Der f 1 emakamelweni okuhlala ezindlu ezine futhi bathola ukuthi ukugxila okumaphakathi kwakungaphansi ngo-63.2% kunalawo asemagunjini okulala.
“Ucwaningo lwase-Australia lwathola izinto eziningi ezingezwani nomzimba kusofa wegumbi lokuhlala.Asizange senze kanjalo.Sayithola embhedeni.Cishe i-gradient yase-Australia-yaseYurophu, ”kusho uButters.
Ngokushesha ngemva komcimbi ngamunye, abacwaningi bavula isihlanzi futhi basisebenzisa ihora le-1. Le nqubo iphindwe izikhathi ezine phakathi nokuvakasha ngakunye, ngenani eliphelele lamahora angu-4 wesampula ekhaya ngalinye.Abacwaningi babe sebehlola ukuthi yini eqoqwe esihlungini.
Nakuba imindeni emi-3 kuphela enamakati kanye nemindeni emi-2 enezinja, imindeni engu-20 iDer f 1, imindeni emi-4 iDer p 1, imindeni eyi-10 Can f 1 kanye nemindeni engu-21 Fel d 1 inani elifanelekayo.
“Cishe kuzo zonke izifundo, eminye imizi ibingenazo izinto ezingezwani nezimbuzane.Ngendlela yethu enhle, sithole izinto ezingezwani nazo yonke indawo,” kusho uButter, ephawula ukuthi isibalo sezinto ezingezwani namakati siyamangaza.
“Mithathu kuphela kwengu-22 imizi enamakati, kodwa izinto ezingezwani namakati zisatholakala yonke indawo,” kusho uButters.” Izindlu ezinamakati azihlali ziyizinto ezingezwani namakati.”
Ingqikithi ye-Der f 1 emoyeni yancishiswa kakhulu (P <.001) ngokuhlunga komoya, kodwa ukuncishiswa kwe-Der p 1 kwakungabalulekile ngokwezibalo, kusho abacwaningi.Ngaphezu kwalokho, inani eliphakathi kwe-Der f 1 lehle ngo-75.2% futhi isamba esimaphakathi se-Der p 1 sehle ngo-65.5%.
Ukuhlunga komoya kuphinde kwehlise ngokuphawulekayo inani eliphelele le-Fel d 1 (P <.01) nge-median engu-76.6% kanye nengqikithi Can f 1 (P <.01) nge-median engu-89.3%.
Ngesikhathi sokuvakasha kokulawula, i-Median Can f1 yayingu-219 pg/m3 yemindeni enezinja kanye no-22.8 pg/m3 yemindeni engenazo izinja. Phakathi nokuvakasha kokungenelela, i-Median Can f 1 yayingu-19.7 pg/m3 yemindeni enezinja kanye no-2.6 pg /m3 yemizi engenazinja.
Ngesikhathi sokuvakasha kokulawula, i-median FeI d 1 count ibingu-50.7 pg/m3 yemindeni enamakati kanye no-5.1 pg/m3 yemindeni engenawo amakati. Phakathi nokuvakasha kokungenelela, imindeni enamakati ibe nesibalo esingu-35.2 pg/m3, kuyilapho imizi engenawo. amakati abe nenani elingu-0.9 pg/m3.
Iningi le-Der f 1 ne-Der p 1 litholwe kuma-PM anobubanzi obungaphezu kwama-microns angu-10 (PM>10) noma phakathi kwama-microns angu-2.5 no-10 (PM2.5-10).Iningi lezinto ezingezwani nekati nezinja nazo zihlotshaniswa nama-PM alaba sayizi. .
Ukwengeza, i-Can f 1 yehliswe ngokuphawulekayo kuzo zonke izilinganiso ze-PM ngokugxila kwe-allergen elinganisekayo, ngokunciphisa okuphakathi kuka-87.5% (P <.01) ku-PM > 10 (P <. <.01).
Nakuba izinhlayiya ezincane ezinama-allergener zihlala isikhathi eside emoyeni futhi zivame ukuhogelwa kunezinhlayiya ezinkulu, ukuhlunga komoya nakho kususa izinhlayiya ezincane ngokuphumelelayo, okuvumela abacwaningi ukuthi basho.Ukuhlunga komoya kuba isu elisebenzayo lokususa izinto ezingezwani nomzimba kanye nokunciphisa ukuchayeka.
“Ukwehlisa i-allergies kubuhlungu bekhanda, kodwa kwenza abantu abangezwani nabo bazizwe bengcono.Le ndlela yokususa izinto ezingezwani nomzimba ilula,” kusho u-Buters, ephawula ukuthi ukunciphisa izinto ezingezwani namakati (azibiza ngokuthi yizigaxa zesine ezinkulu) kunzima kakhulu.
"Ungaligeza ikati - inhlanhla - noma ukuxosha ikati," esho."Ayikho enye indlela engiyaziyo yokususa izinto ezithinta ikati.Ukuhlunga komoya kuyakwenza.”
Okulandelayo, abacwaningi bazohlola ukuthi ingabe abaphethwe yi-allergies bangalala kangcono yini ngesicoci somoya.
Isikhathi sokuthumela: May-21-2022